This collection is made up of records of the various agencies of the church. It also includes material regarding local churches and annual conferences. The collection is made up of thirteen series. The three largest series which make up the bulk of the collection are the Missionary Society, the Woman's Missionary Society, and the Board of Christian Education.

This collection contains mostly administrative records from Williams' work in missions administration. Included are Williams' reports on his trips overseas; personnel application procedures and personnel development procedures; papers and reports by other authors on missiology and missions theory; a history of the Joint Committee on Missionary Personnel: clippings, books, pamphlets, and reports on several geographic regions, especially China.

This collection is made up of the administrative material from the Board of Missions. It also includes the records of the World Mission Division, the Division of Home Missions and Church Extension and its various departments and mission fields, the National Missions Division and the Mission Advance Program. The collection is made up of six series. Although there is some material from 1862 and the 1970's, the bulk of the material is from 1946 to 1968.