This collection is made up of the administrative material from the Board of Missions. It also includes the records of the World Mission Division, the Division of Home Missions and Church Extension and its various departments and mission fields, the National Missions Division and the Mission Advance Program. The collection is made up of six series. Although there is some material from 1862 and the 1970's, the bulk of the material is from 1946 to 1968.

The Walter Russell Lambuth collection reflects the Bishop's activities outside the United States in a series of manuscripts, articles and letters. There is one typed manuscript of his book, Medical Missions: The Twofold Task. There is a good chance that most, if not all, of the other typed manuscript articles of Lambuth's trips around the world were published by the Southern Methodist Church in their various periodicals. The correspondence is addressed to family, friends, colleagues and associated groups. Clippings are either death notices and/or tributes for both Lambuth and his wife.