When the Church of the United Brethren and the Evangelical Church merged in 1946, the Home Mission and Church Erection Society, the Foreign Missionary Society, and the Women's Missionary Association of the Church of the United Brethren in Christ, and the Missionary Society, Women's Missionary Society, and the Board of Church Extension of the Evangelical Church were united to form the Board of Missions of the Evangelical United Brethren Church.
When the Evangelical United Brethren Church and the Methodist Church merged in 1968, the boards of missions of both churches were united to form the Board of Missions of the United Methodist Church. In 1972, the Board of Missions became the Board of Global Ministries and in 1976 was renamed the General Board of Global Ministries which it is still called today.