This collection is made up of records of the various agencies of the church. It also includes material regarding local churches and annual conferences. The collection is made up of fourteen series. The four largest series which make up the bulk of the collection are the Woman's Missionary Society, Missionary Society, Annual Conferences, and Sunday School and Tract Union.

This collection is made up of administrative material from the Foreign Missionary Society and its various mission fields. It also includes material regarding the 1898 Sierra Leone massacre of missionaries and the trial of Daniel F. Wilberforce for cannibalism.